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Vibramycin: General Information

Vibramycin - Medicines | Tetracyclines

Tetracyclines have at least a broad spectrum of action than the aminoglycosides (when bacteristatic mechanism of action).

Along with the biosynthetic drugs (tetracycline, oxytetracycline) oral dosage forms for release in / in the introduction - morfociklin, oxyglukociklin and semisynthetic derivatives - metaciklin (rondomicin), doxycycline (Vibramycin).

Tetracycline - relatively low-toxic drugs, but in high doses they can cause fatty degeneration of the liver and kidneys (second). Tetracyclines with oral mucosa irritating to the gastrointestinal tract, inhibiting the function of the digestive glands, vitamins synthesis in the intestine.

Tetracyclines are concentrated in the bones. In childhood, they affect the growth and development of teeth, so up to 8 years of age tetracyclines is not indicated. In connection with a reduction in sensitivity to tetracycline Staphylococcus is widely used in combination with oleandomycin, erythromycin and chloramphenicol.

Of considerable interest is a semi-synthetic drug oxytetracycline doxycycline (Vibramycin). Not actively other derivatives.

Vibramycin 100mg can be used in patients in inhibition of kidney function (including dialysis)

The dose of tetracycline, oxytetracycline for intake of at least 1 g / day in equal doses (after 6 h) methacycline 600 - 900 mg / day, and doxycycline 200 mg on the first day, followed by 100 mg / day.

Duration of treatment up to 3 weeks. Intravenous drugs are administered 0.15 - 0.3 g of 2 - 3 times per day. For the prevention of dysbiosis to simultaneously appoint nystatin or Levorinum, as well as products containing lactic acid bacteria.

Pharmacotherapy of mycoplasma and ureaplasma

Vibramycin of choice are antibiotics active against mycoplasmas.

Ureaplasmosis

Treatment is carried out taking into account the phase of the inflammatory process:

  • in acute inflammation of a fairly ureaplazmoz drugs and other therapies associated infections (if any);
  • subacute forms sanitize complex products using local therapy;
  • chronic or indolent fresh forms are pursuing a comprehensive immunostimulation therapy (Methyluracilum inward pirogenal, prodigiozan intramuscular injection) in combination with local therapy.

After 7-8 days reduced the intensity of local therapy, amid ongoing immunostimulation appoint one of ureaplasmosis drugs. Selection drugs with biological pathogens determined by the characteristics, their in vitro sensitivity and in vivo.

In clinical practice, use the following antibiotic regimens ureaplasmosis genital tract in couples (general treatment):

Doxycycline (Vibramycin) - 100 mg 2 times a day for 10 days, at a dose rate - 2.0 g; or the first loading dose - 200-300 mg, more - 0.1 g 2 times a day, a rate of 3.0 g 2,0, erythromycin - 500 mg four times a day for 2 weeks;

Tetracycline (main drug most widely used) - 0.5 g 4 times a day for 1-2 weeks, or 0.3 g of 5 times a day (10 to 12 days), course dose - to 27.0 g. For repeat prescribed erythromycin - 0.5 g 4 times a day for 7 days. Mandatory protection of Nystatin and vitamins.

Gentamicin administered - 40 mg every 8 hours for 5-7 days, only rate - 600-840 mg (as monotherapy) or in the same dose in combination with doxycycline (0.1 g three times a day for a course - 2.5 g).

Psittacosis in humans - symptoms, infection, prevention and treatment

Vornitoz is an acute infectious disease, because that can affect the central nervous system, the lungs, there is a fever, intoxication, increasing the size of the spleen and liver. When a pathogen enters the human body with the environment, he can live there intracellularly to 3 weeks. To catch psittacosis can be from domestic or wild birds - turkey, urban pigeons, parrots, ducks and canaries. Treat people who constantly come in contact with birds - poultry farm and slaughterhouse workers. Psittacosis is typical for the cold time of year, because this person becomes infected.

Psittacosis can escalate into an epidemic. The pathogen can penetrate by inhalation of dust, which consists of small particles from bird feces. It is also possible to catch the disease after a person inhales particles down sick birds. Sick psittacosis is not dangerous for the environment, because it is not necessary to urgently hospitalize the patient and isolate from other people.

What happens in the human body due to infection psittacosis?

Chlamydia is passed through the protective barriers, and still ended up in the human body due to inhalation of respiratory tract. Then they start to penetrate into the bronchi and bronchioles, alevoly then, because of this inflammatory process begins. Pathogens multiply in the cells, if time does not diagnose the disease, they can get into the bloodstream, there is intoxication undertaking, affects various organs and systems - the adrenal glands and the central nervous system.

To poison people can toxins due culprit psittacosis. The infection can enter the human body through the digestive tract. The symptoms of psittacosis at the same, but there is pneumonia, which develops due to infection aerogenic nature.

After the man once been ill with psittacosis, a person produces lifelong immunity, but it is not persistent, because may be the recurrence of the disease. Only through comprehensive prevention psittacosis, regular check-ups of workers at poultry farms and other enterprises that are engaged in birds.

Vibramycin: Treatment of psittacosis in humans

For treatment are appointed by antibiotics - doxycycline vibramitsin tetracycline.

The treatment is continued until one week before last, while human body temperature begins to fall, and then another 10 days of treatment is necessary to achieve a positive result.

If the patient does not tolerate tetracycline, they can be replaced by erythromycin and chloramphenicol. They are not as effective and the recovery may be delayed.

When the disease occurs in an acute form, oxygen therapy may be applied, it uses oxygen, vitamin preparations. When the body is restored, autohaemotherapy used for this subcutaneously or intramuscularly injected blood that is taken from a vein. With this method of treatment, and rehabilitation can strengthen the body's defense mechanisms.

Prevention psittacosis

It is important to timely detect in advance the infection in poultry, for it to carry out all the sanitary and veterinary measures on all bird enterprises.

It is necessary to carefully check the imported products, not to forget for quarantine measures. Prevention psittacosis help protect against the disease because there is no special vaccine.

So, psittacosis refers to the acute form of the disease, because of which the central nervous system of a person and his lungs can be affected. The source of the disease are wild and domestic birds. The infection is transmitted through everyday contact and when a person is infected through everyday objects; the airborne route, when inhaled particles; fecal-oral route, if used contaminated food.

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