Doxycycline - description of the antibiotic and its spectrum
Doxycycline - description of this modern semisynthetic tetracycline antibiotic indicates that it has a broad spectrum of activity, but unlike other drugs in this group (including tetracycline itself) differ much less toxicity.
Features of action of doxycycline.
Doxycycline - today is a popular semi-synthetic antibiotic tetracycline. The peculiarity of its action is that having the same action mechanism as that of other antibiotics of this group (inhibition of protein metabolism in cell membranes bacterial pathogens infections, including those located intracellularly) has a higher efficiency and lower toxicity.
High antimicrobial activity allows for the drug in doses several times smaller than a number of other antibiotics (such as natural antibiotics tetracycline and oxytetracycline), which significantly reduces its toxic effect on the body, especially the liver.
A feature of doxycycline is also more complete intestinal absorption and longer duration of action.
The popularity of this drug today is also due to the fact that it is effective against such pathogens located intracellularly infections such as Chlamydia, Mycoplasma and Ureaplasma, which are often the cause of long-term infection and inflammatory processes.
Doxycycline is active against many Gram-positive and Gram-negative microorganisms are the cause of upper respiratory tract infections, respiratory system, biliary tract and digestive organs, kidneys and urinary tract, eyes, skin, soft tissues, bones and joints.
Doxycycline is also effective with regard to the agents of especially dangerous infections, such as cholera, plague, anthrax, tularemia. It is successfully used in dysentery and other intestinal infections of bacterial origin, whooping cough, syphilis, gonorrhea, brucellosis, yersiniosis, malaria and other infections.
Doxycycline under different names (vibramitsin, doksibene, tetradoks, JUnidoks soljutab and others) produce different pharmaceutical companies in a variety of dosage forms - tablets, capsules, syrup, and the freeze-dried for solution for infusion.
What medications is used to treat bacterial vaginosis. Antibiotics pills, medicine, candles from bacterial vaginosis
By the choice of drugs for the treatment of bacterial vaginosis should be approached very seriously. Wrong choice of the drug can only aggravate the process and lead to numerous complications. Know about what drugs to treat gardnerella should every woman that has not spared this unpleasant disease, but they have the right to appoint only a doctor who has studied the results of diagnostics and knowing the patient's history and characteristics of the organism.
When choosing a medication for the treatment of gardnerelly need to consider a number of factors that will ensure rapid recovery. Before the doctor will determine how to treat gardnerella and what drugs are used, the patient passes smear. Depending on the amount of virus in secretions from the vaginal microflora status, gynecologist chooses a corresponding cure bacterial vaginosis. The most common drug in the fight against bacterial vaginosis most physicians and patients considered metronidazole. This compound actually has an active effect against many pathogens, but not all, it is well tolerated treatment for Gardnerella therefore perfect and other drugs that are available in the form of tablets and suppositories or gels.
Only a doctor will be able to choose the right medicine for gardnerelly if the disease has turned into a chronic form or had some complications. by results of diagnostics specialist sees whether secretions present in other organisms, which can cause sexually transmitted diseases. There are drugs for bacterial vaginosis that can simultaneously affect several groups of microorganisms, so it is reasonable to use one such pill from Gardnerella and Candida or Chlamydia than independently appoint a few drugs that will aggravate dysbiosis.
Special treatment requires a pregnant woman who often develop bacterial vaginosis. Not all drugs are allowed on gardnerelly those bears in its body a little life. Especially dangerous is the use of tablets of metronidazole from bacterial vaginosis in the first trimester of pregnancy. Expectant mothers can be treated using candles, but only on doctor's prescription and under his watchful constant surveillance.
Antibiotics for treating bacterial vaginosis
Although antibiotics are often the cause of dysbiosis in the vagina, to do without these funds in the fight against gardnerellezom it is almost impossible. If smears gardnerella detected, treatment with antibiotics is inevitable. Microorganisms, which are harmful to the vagina and create there a disgusting fishy smell, must be destroyed, and a better and more effective than antibiotics for bacterial vaginosis, prescribe in such cases is not easy. They are prescribed as for acute forms of the disease, and upon detection of low-grade infection that is chronic. 90% of cases of disease are cured with a correct choice of the preparation. The greatest effect is treatment if tablets are assigned at the beginning of the disease. Then the next stage of the struggle with the disease will be aimed at the restoration of the number of lactobacilli in the microflora. The duration of treatment will depend on how fast is reduction in the number of harmful microorganisms in the vagina.
Not all antibiotics for bacterial vaginosis are effective. To make the right choice of drug, a gynecologist to establish an accurate diagnosis offers to surrender not only the analysis of urine or blood, but be sure to appoint a culture gardnerella crop on sensitivity to antibiotics. Since vaginosis creates favorable conditions for the breeding of many microorganisms, that further checks for the presence of chlamydia, hepatitis viruses or mycoplasma to begin treatment at the same time.
Determining which antibiotics are suitable for the treatment of gardnerelly, the doctor takes into account the condition of the patient, so the choice for each patient is an individual. Virtually every drug has its contraindications. While some patients do not feel them at all, while others can not afford such an antibiotic from gardnerelly as doxycycline, because it will certainly cause them strong indigestion or development of thrush.
After treatment with antibiotics necessarily any need to restore microflora and strengthening the immune system, otherwise relapse is inevitable. Correction of power, proper hygiene - a good preventive and good helpers in the fight against non-venereal vaginal infections.
Doxycycline for bacterial vaginosis
Doxycycline with bacterial vaginosis - a rather effective drug. It may appoint a gynecologist after the detection sensitivity to this antibiotic gardnerelly received the results of the culture seeding.
Doxycycline Tablets are one of the drugs of the tetracycline group. The range of its application is so broad, it is impossible to doubt the effective help of this tool. Belonging to tetracyclines indicates that the basic substance which is a part of the drug, provided tetracycline, but its molecule was modified by synthesis, so when a new medication preparation degree diseases convalescence patients is much higher. Applied tablets a day from 100 to 200 mg. The dosage will determine after the diagnosis of the doctor. Doxycycline is produced in powder form for injection, but in a form vaginosis is not used.
The use of doxycycline at gardnerella almost always justified, because the disease goes away in a short time and complications do not arise. No doctor does not appoint an agent to children under 12 years, women in the state. If you have problems with the stomach doxycycline have to be replaced.
Azithromycin for bacterial vaginosis
In the treatment of diseases, sexually transmitted diseases and affecting the reproductive system, azithromycin taken its worthy place. But whether azithromycin is effective for bacterial vaginosis, doctors continue to debate for quite a long time, bringing the issue up for discussion at the meetings venereologists luminaries.
Available exclusively in the form of azithromycin tablets. When ingested, it is rapidly absorbed into the blood and can accumulate in the outbreak of the disease, making it a fairly high concentration of active substances. This reduces the amount of bacterial vaginosis, but microflora in such treatment suffers. If you can not assign a different drug for bacterial vaginosis, the azithromycin should be used very carefully and strictly according to the dosage. treatment in such cases, up to five days. Immediately after taking the drug should be to rebuild the number of lactobacilli.
Do not risk with taking azithromycin: pregnant women, nursing mother or persons who have kidney disease or liver. Invalid combination of agents with heparin.
Metronidazole for patients with bacterial vaginosis may be administered as a topical treatment and oral medication. Topical therapy involves the use of a gel or candles that at night or in the morning and evening with a large amount of virus introduced into the vagina. In tablets requires two receiving means within one day. When using local resources to get rid of the virus less severe side effects. The peculiarity of bacterial vaginosis with metronidazole treatment is that the substance in any form made does not allow the use of even a weak alcohol, causing antabuspodobny syndrome.
Metronidazole is effective for bacterial vaginosis due to its effects on anaerobic microorganisms with the destruction of their DNA structure. Immediately after taking the observed its high penetrating power. The maximum substance concentration in the blood is not achieved, and in the centers of clusters of virus. Displayed substance primarily through the kidneys.
Not recommended and not allowed specialists metronidazole treatment of bacterial vaginosis in women who are breast-fed infants or nurture a child, while in the first trimester of pregnancy. In subsequent fetal development timeline use of the drug under the control and supervision of the gynecologist is allowed, if the infection is threatening during pregnancy.
Tinidazole is able to influence the Gardnerella, which affects the genitourinary system. Having a high lipophilicity ratio antiprotozoal drug is rapidly absorbed from the gastrointestinal tract, it spreads throughout the body with blood and concentrated in places of accumulation of infection. When a virus destroys the structure of DNA synthesis and inhibits pathogen. Actively builds up in the area of development of dysbiosis and excreted primarily through the kidneys. Like all drugs of this group, it passes through the liver, so tinidazole with bacterial vaginosis do not take patients who have problems with that body.
The course of treatment with the help of bacterial vaginosis tinidazole chooses doctor. It can be offered a four-day therapy, designed to receive 6 g of the drug. accepted in the first two days with 2 g of the drug per 1 time, the rest remaining dose is divided into 2 to 0.5 g of the day, 2 times a day. In chronic bacterial vaginosis may be extended tinidazole treatment up to 10 days.
Not recommended tinidazole for pregnant women, lactating mothers, patients with impaired hematopoiesis and damage to the nervous system. The medicine of many incompatible with alcohol. It leads to the appearance disulfiramopodobnyh effect.
One of the most popular drugs for the topical treatment of bacterial vaginosis are considered candles. These medications are composed of the same active ingredients as the pills. Their effects on the more gentle. Their effect is that they can create an optimal physiological environment of the vagina sick woman, helping to reduce the amount of harmful viruses. Vaginal candles against gardnerelly prescribed to pregnant women to treat the disease closer to birth.
Effective considered candles from bacterial vaginosis with metronidazole or tinidazole. Usually, they are administered in the vagina for 2 to 3 hours in the morning and (or) the evening. The course of treatment candles gardnerelly lasts at least 7 days. It is not necessary to use some candles from gardnerelly in the critical days for women. Initiate therapy with the use of suppositories best through 1- 2 days after the end of menstruation.